Post-polio syndrome (PPS), a progressive neuromuscular syndrome that primarily affects women, occurs 10-40 years after recovery from an acute polio infection. Risk for developing this syndrome depends on initial damage to motor neurons during the polio infection, which can lead to neurologic damage, muscle atrophy, pain, weakness, and respiratory and speech impairments. Management of women with PPS requires a multidisciplinary approach that entails both pharmacologic and non-pharmacologic therapies. Nurse practitioners may not have learned about this disease during their educational years, or they may have learned about it many years ago, and therefore require up-to-date information about the clinical presentation of PPS in order to lead a team that will manage these patients’ care and treatment plans. The authors provide an overview of PPS with regard to pathophysiology, clinical manifestations, diagnosis, and treatment.
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